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Can I read Liquid Chromatography with Amperometric Detection for the Determination of Non-steroidal Anti-inflammatory Drugs in Plasma on EtoBox?
Liquid Chromatography with Amperometric Detection for the Determination of Non-steroidal Anti-inflammatory Drugs in Plasma by Amir G Kazemifard; Douglas E Moore is a Chemistry article available to read on EtoBox.
What is Liquid Chromatography with Amperometric Detection for the Determination of Non-steroidal Anti-inflammatory Drugs in Plasma about?
A simple and sensitive hquid chromatographic method with electrochemical detection IS descrtbed for the quantitative determmation of the non-steroidal anti-mfammatory drugs ddiumsal, mdomethacm, naproxen, piroxicam and sulmdac m human plasma Isolation of the drug from the biological fluid is achieved usmg a Sep-pak RP18 cartridge Separation of plasma components occurs on a reversed-phase C,, column with a mobile phase consistmg of methanol-water-phosphate buffer For the amperometric detection the potential of + 0 9 V was set on the working electrode The detection limit of the assay is l&20 ng/ml The method showed good concordance for plasma samples contammg the drugs (r = 0 999) and can be readily utilized for chmcal pharmacokmetic studies.
Who reads Liquid Chromatography with Amperometric Detection for the Determination of Non-steroidal Anti-inflammatory Drugs in Plasma?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Amir G Kazemifard; Douglas E Moore
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0378-4347)
- Published
- 1990
- Language
- EN
- Field
- Chemistry (Physical Sciences)