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Dermatopathologic features of cutaneous squamous cell carcinoma and actinic keratosis: Consensus criteria and proposed reporting guidelines by Rachel E. Christensen; Dirk M. Elston; Brandon Worley; McKenzie A. Dirr; Noor Anvery; Bianca Y. Kang; Soon Bahrami; Robert T. Brodell; Lorenzo Cerroni; Carly Elston; Tammie Ferringer; M. Yadira Hurley; Kyle Garton; Joyce Siong See Lee; Yeqiang Liu; John C. Maize; Jennifer M. McNiff; Ronald P. Rapini; Omar P. Sangueza; Christopher R. Shea; Cheng Zhou; Murad Alam is a Medicine article available to read on EtoBox.

What is Dermatopathologic features of cutaneous squamous cell carcinoma and actinic keratosis: Consensus criteria and proposed reporting guidelines about?

Background There is considerable variation in the literature regarding the dermatopathologic diagnostic features of and reporting guidelines for actinic keratosis (AK) and cutaneous squamous cell carcinoma (cSCC). Objective To develop consensus recommendations regarding diagnostic criteria, nomenclature, and reporting of AK and cSCC. Methods Literature review and cross-sectional multiround Delphi process including an international group of expert dermatopathologists followed by a consensus meeting. Results Consensus was achieved regarding the key dermatopathologic features necessary for diagnosing cSCC, AK, and associated variants; grading of degree of cellular differentiation in cSCC; utility of immunohistochemistry for diagnosis of cSCC; and pathologic features that should be reported for cSCC and AK. Limitations Consensus was not achieved on all questions considered. Conclusion Despite the lack of clarity in the literature, there is consensus among expert dermatopathologists regarding diagnostic criteria and appropriate reporting of AK and cSCC. Widespread implementation of these consensus recommendations may improve communication between dermatopathologists and clinicians, faci

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Author

Rachel E. Christensen; Dirk M. Elston; Brandon Worley; McKenzie A. Dirr; Noor Anvery; Bianca Y. Kang; Soon Bahrami; Robert T. Brodell; Lorenzo Cerroni; Carly Elston; Tammie Ferringer; M. Yadira Hurley; Kyle Garton; Joyce Siong See Lee; Yeqiang Liu; John C. Maize; Jennifer M. McNiff; Ronald P. Rapini; Omar P. Sangueza; Christopher R. Shea; Cheng Zhou; Murad Alam

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Medicine (Health Sciences)