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Do Not Discriminate Only on Age for Cardiovascular Risk Management! by Fabrice M. A. C. Martens is a Medicine article available to read on EtoBox.

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## Does cardiovascular risk management (CVRM) still have benefits in older patients? In most of the larger cardiovascular studies the real elderly patients are not included. Also the possible therapy duration is shorter, while all cardiovascular (CV) risk reduction graphs show divergence in treatment time, regardless of the therapy, giving an increasing reduction in risk with an increased duration of treatment. Furthermore, the risk of side effects could be higher in older patients. So CVRM in older patients has been debated for decades. However, mainly the elderly (75-95 years) suffer from cardiovascular disease and there is substantial evidence in pharmacological as well as in Mendelian randomisation studies that 'the longer/earlier the lower LDL cholesterol, the better it is, despite which treatment regime' [1]. The most recent meta-analysis by the Cholesterol Treatment Trialists' Collaboration showed that even patients aged > 75 years have benefit [2] without side effects on cognition [3]. Strict blood pressure control in the elderly was even more of a dispute for years because of the known U-shape curve in cardiovascular benefits and the obvious side effects when the blood pre

Who reads Do Not Discriminate Only on Age for Cardiovascular Risk Management!?

Author

Fabrice M. A. C. Martens

Publisher

Bohn Stafleu van Loghum

Published

2023

Language

EN

Field

Medicine (Health Sciences)