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Can I read Vaccination against Fasciola hepatica infection using a Schistosoma mansoni defined recombinant antigen, Sm14 on EtoBox?
Vaccination against Fasciola hepatica infection using a Schistosoma mansoni defined recombinant antigen, Sm14 by Marília S. Almeida; Humberto Torloni; Paulo Lee-Ho; Monica M. Vilar; Nilton Thaumaturgo; Andrew J. G. Simpson; Miriam Tendler is a Medicine article available to read on EtoBox.
What is Vaccination against Fasciola hepatica infection using a Schistosoma mansoni defined recombinant antigen, Sm14 about?
## SUMMARY Fasciola hepatica __is the causative agent of fasciolosis in many areas in America, Europe, Africa, Asia and Australia. There is an urgent need for improved methods to control the parasite's transmission. We describe the use of an experimental vaccine based on a recombinant antigen cloned from another parasite,__ Schistosoma mansoni __(Sm14), that induces high levels of cross protection in mice against both__ S. mansoni __and__ F. hepatica. __Sheep and mice vaccinated with Sm14 were significantly protected against challenge infection with metacercariae of__ Fasciola hepatica __and were completely free of the histopathological hepatic damage related to liver fluke infection. The vaccine will provide a valuable new tool to aid in transmission control of this economically important disease__.
Who reads Vaccination against Fasciola hepatica infection using a Schistosoma mansoni defined recombinant antigen, Sm14?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Marília S. Almeida; Humberto Torloni; Paulo Lee-Ho; Monica M. Vilar; Nilton Thaumaturgo; Andrew J. G. Simpson; Miriam Tendler
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley; FASEB (ISSN 0141-9838)
- Published
- 2003
- Language
- EN
- Field
- Medicine (Health Sciences)