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The effect of low-level light therapy on orthodontic tooth movement rate, heat shock protein 70, and matrix metallopreteinase 8 expression: Animal study by IdaBagus Narmada; Muhammad Rubianto; SuhartonoTaat Putra is a Dentistry article available to read on EtoBox.

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## Background: The aim of this study was to determine the effect of low-level light therapy (LLLT) on orthodontic tooth movement (OTM) rate, heat shock protein 70 (HSP-70) expression, and matrix metalloproteinase 8 (MMP-8) expression. ## Materials and Methods: In this experimental study twenty-four male guinea pigs were randomly divided into three groups (__n__ = 8): control group (K) without orthodontic force and LLLT; treatment group 1 (T1) with orthodontic force, and treatment group 2 (T2) with orthodontic force and LLLT. The labial surfaces of both maxillary central incisors in treatments groups were installed with single-wing bracket before being inserted with close coil spring to give 10 g/cm^2^ orthodontic force. For the T2 group, 4 J/cm^2^ of LLLT was administered in the mesial-distal and labial-palatal regions for 3 min every day. On day 14, the gap between teeth was measured and immunohistochemistry staining was done to determine HSP-70 and MMP-8 expression. Data were analyzed using (IBM, New York, (ANOVA), followed by Turkey's HSD test to determine the differences between groups. Nonnormal distributed data would be analyzed using Kruskal–Wallis test, followed by Mann–Whi

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Author

IdaBagus Narmada; Muhammad Rubianto; SuhartonoTaat Putra

Publisher

Medknow

Published

2020

Language

EN

Field

Dentistry (Health Sciences)