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5 Metabolic Changes of Drugs and Related Organic Compounds by gakygollea is a document available to read on EtoBox.
Secondary amines are primarily metabolized through oxidative N-dealkylation, oxidative deamination, and N-oxidation, leading to the formation of primary amine metabolites. Primary amines undergo oxidative deamination via monoamine oxidases and can also be transformed by N-oxidation, with distinct pathways for aromatic and aliphatic amines. The document discusses the metabolic processes and examples of various amines, highlighting the significance of oxidative pathways in drug metabolism.
- Author
- gakygollea
- Language
- EN