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No Association Between Non-steroidal Anti-inflammatory Drugs and Acute Appendicitis in a Case–control Study by J. M. M. Evans; A. M. MacGregor; F. E. Murray; K. Vaidya; A. D. Morris; Dr. T. M. MacDonald is a Medicine article available to read on EtoBox.
What is No Association Between Non-steroidal Anti-inflammatory Drugs and Acute Appendicitis in a Case–control Study about?
## Background: A recent case-control study reported an association between non-steroidal anti-inflammatory drug (nsaid) use and acute appendicitis. this association was investigated in a case-control study of patients, aged 30 years and over, admitted as an emergency to hospitals in tayside between 1989 and 1992, who had appendicectomy for acute appendicitis. ## Methods: A record-linkage database containing records of dispensed prescriptions and hospital admissions was used. a total of 223 patients were identified. the medical records of 161 were checked, of which 138 were valid cases, and information on white cell count and nsaid exposure was recorded. community and hospital controls were generated. ## Results: Some 9.0 per cent of patients were prescribed nsaids within 90 days of hospitalization, compared with 7.6 per cent of community controls and 11.5 per cent of hospital controls. the odds ratio was 1.21 (95 per cent confidence interval 0.73-2.01) and 0.75 (0.43-1.32) respectively. there was no significant difference in white cell count between exposed and non-exposed cases. no increased risk of appendicectomy was associated with aspirin use: odds ratio 1.67 (0.52-5.30) and 0.
Who reads No Association Between Non-steroidal Anti-inflammatory Drugs and Acute Appendicitis in a Case–control Study?
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- Author
- J. M. M. Evans; A. M. MacGregor; F. E. Murray; K. Vaidya; A. D. Morris; Dr. T. M. MacDonald
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square; Oxford University Press (OUP) (ISSN 0007-1323)
- Published
- 1997
- Language
- EN
- Field
- Medicine (Health Sciences)