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Can I read Quantifying the Rates of Late Reactivation Tuberculosis: a Systematic Review on EtoBox?
Quantifying the Rates of Late Reactivation Tuberculosis: a Systematic Review by Katie D Dale; Malancha Karmakar; Kathryn J Snow; Dick Menzies; James M Trauer; Justin T Denholm is a Medicine article available to read on EtoBox.
What is Quantifying the Rates of Late Reactivation Tuberculosis: a Systematic Review about?
The risk of tuberculosis is greatest soon after infection, but Mycobacterium tuberculosis can remain in the body latently, and individuals can develop disease in the future, sometimes years later. However, there is uncertainty about how often reactivation of latent tuberculosis infection (LTBI) occurs. We searched eight databases (inception to June 25, 2019) to identify studies that quantified tuberculosis reactivation rates occurring more than 2 years after infection (late reactivation), with a focus on identifying untreated study cohorts with defined timing of LTBI acquisition (PROSPERO registered: CRD42017070594). We included 110 studies, divided into four methodological groups. Group 1 included studies that documented late reactivation rates from conversion (n=14) and group 2 documented late reactivation rates in LTBI cohorts from exposure (n=11). Group 3 included 86 studies in LTBI cohorts with an unknown exposure history, and group 4 included seven ecological studies. Since antibiotics have been used to treat tuberculosis, only 11 studies have documented late reactivation rates in infected, untreated cohorts from either conversion (group 1) or exposure (group 2); six of these
Who reads Quantifying the Rates of Late Reactivation Tuberculosis: a Systematic Review?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Katie D Dale; Malancha Karmakar; Kathryn J Snow; Dick Menzies; James M Trauer; Justin T Denholm
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)