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High levels of maternal folate have been linked to negative neurological outcomes in offspring such as autism spectrum disorder (ASD). Five studies were reviewed that examined the relationship between high maternal folate intake during pregnancy and outcomes in children. Two animal studies found that high folic acid supplementation was associated with impaired short-term memory and decreased hippocampus size in mice offspring. Three human studies found that very high maternal folate levels (>60.3 nmol/L) we

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api-536652711

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