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Depression in multiple sclerosis: Is one approach for its management enough? by C. Danielle Jones; Robert Motl; Brian M. Sandroff is a Medicine article available to read on EtoBox.

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## Background: Major depression disorder (mdd) and severe depression symptoms are highly prevalent in multiple sclerosis (ms). depression can worsen symptoms of ms and is associated with significantly reduced quality of life and increased risk of suicide. currently, there is no gold-standard, single treatment available for depression in ms. pharmacotherapy, cognitive behavior therapy (cbt), and exercise training individually are moderately, yet incompletely, efficacious for managing depression in the general population and ms. ## Purpose: This review provides an overview of evidence from meta-analyses and systematic reviews for current treatments of depression in persons with ms. this review further develops the rationale for using a combinatory treatment approach in persons with ms. ## Methods: We performed a narrative review of meta-analyses and systematic reviews regarding the current state of evidence for the three most common treatments of depression in persons with ms (i.e., antidepressant medication, cognitive-behavior therapy, and exercise training). we provide a concise assessment of the overall effect of these treatments on depression in the general population and then pe

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Author

C. Danielle Jones; Robert Motl; Brian M. Sandroff

Publisher

Elsevier BV

Published

2021

Language

EN

Field

Medicine (Health Sciences)