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The role of local inflammation in complications associated with intubation in pediatric patients: A narrative review by Sebastian Amaya; Marcelino Murillo; Martha L. Gutiérrez Pérez; Hector S. Cervera; María J. Andrade; María A. Zuñiga; Natalia Barreto; María I. Daza; Luisa F. Carvajal; Catalina M. Alarcón; Laura Aponte; Vanessa A. Olbrecht is a Medicine article available to read on EtoBox.

What is The role of local inflammation in complications associated with intubation in pediatric patients: A narrative review about?

Although the most important primary local inflammatory response factor to intubation is not yet clear, it is known that it may be directly attributed to the presence of trauma during intubation or the response of oral bacterial flora present in the trachea. It is known that prolonged intubation is associated with worse outcomes, but other underlying systemic issues, such as sepsis and trauma, are also associated with this result. Likewise, patients who require advanced airway management and excessive manipulation are more likely to experience complications. There are various inflammatory mediators that are generated during orotracheal intubation, many of which can be considered targets for therapies to help reduce inflammation caused by intubation. However, there is little evidence on the management of the inflammatory response induced by orotracheal intubation in pediatric patients. Therefore, the aim of this narrative review is to highlight the intubation associated complications that can arise from poorly controlled inflammation in intubated pediatric patients, review the proposed pathophysiology behind this, and discuss the current treatments that exist. Finally, taking into ac

Who reads The role of local inflammation in complications associated with intubation in pediatric patients: A narrative review?

Author

Sebastian Amaya; Marcelino Murillo; Martha L. Gutiérrez Pérez; Hector S. Cervera; María J. Andrade; María A. Zuñiga; Natalia Barreto; María I. Daza; Luisa F. Carvajal; Catalina M. Alarcón; Laura Aponte; Vanessa A. Olbrecht

Publisher

Wiley

Published

2023

Language

EN

Field

Medicine (Health Sciences)