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Can I read Inositol 1,4,5-Trisphosphate Receptors in Human Disease: A Comprehensive Update on EtoBox?
Inositol 1,4,5-Trisphosphate Receptors in Human Disease: A Comprehensive Update by Gambardella, Jessica; Lombardi, Angela; Morelli, Marco Bruno; Ferrara, John; Santulli, Gaetano is a Medicine article available to read on EtoBox.
What is Inositol 1,4,5-Trisphosphate Receptors in Human Disease: A Comprehensive Update about?
Inositol 1,4,5-trisphosphate receptors (ITPRs) are intracellular calcium release channels located on the endoplasmic reticulum of virtually every cell. Herein, we are reporting an updated systematic summary of the current knowledge on the functional role of ITPRs in human disorders. Specifically, we are describing the involvement of its loss-of-function and gain-of-function mutations in the pathogenesis of neurological, immunological, cardiovascular, and neoplastic human disease. Recent results from genome-wide association studies are also discussed.
Who reads Inositol 1,4,5-Trisphosphate Receptors in Human Disease: A Comprehensive Update?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Gambardella, Jessica; Lombardi, Angela; Morelli, Marco Bruno; Ferrara, John; Santulli, Gaetano
- Publisher
- Multidisciplinary Digital Publishing Institute (MDPI) (ISSN 2077-0383)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)