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Prevalence of specific types of human papillomavirus and cervical squamous intraepithelial lesions in consecutive, previously unscreened, West-African women over 35 years of age by Long Fu Xi; Papa Touré; Cathy W. Critchlow; Stephen E. Hawes; Birama Dembele; Papa Salif Sow; Nancy B. Kiviat is a Medicine article available to read on EtoBox.

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## Abstract Previous studies among women worldwide have demonstrated that infection with specific types of human papillomaviruses (HPV) is central to the pathogenesis of cervical neoplasia. There is little data, however, concerning the prevalence of specific HPV types and the association of each type with cervical neoplasia among women in sub‐Saharan Africa, who remain at very high risk of cervical cancer. We studied 2,065 consecutive patients aged 35 years or older, presenting to community health clinics in Dakar and Pikine, West Africa, who had not been screened previously for cytologic abnormalities or HPV. Cytologic diagnosis and HPV detection were accomplished using a ThinPrep Pap and a polymerase chain reaction‐based reverse‐line strip assay, respectively. Odds ratios (OR) and associated 95% confidence intervals (CI) were estimated using polynomial logistic regression. Cytologic abnormalities were found in 426 women (20%), including 254 (12%) with atypical squamous cells of undetermined significance, 86 (4%) with low‐grade squamous intraepithelial lesions, 66 (3%) with high‐grade squamous intraepithelial lesions (HSIL) and 20 (1%) with invasive cancer. HPV infection was detec

Who reads Prevalence of specific types of human papillomavirus and cervical squamous intraepithelial lesions in consecutive, previously unscreened, West-African women over 35 years of age?

Author

Long Fu Xi; Papa Touré; Cathy W. Critchlow; Stephen E. Hawes; Birama Dembele; Papa Salif Sow; Nancy B. Kiviat

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square; Test accounts (ISSN 0020-7136)

Published

2002

Language

EN

Field

Medicine (Health Sciences)