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Norepinephrine and Epinephrine Complexation by Jun Wei is a document available to read on EtoBox.
This study investigates the inclusion complexation behavior of norepinephrine (NORE) and epinephrine (EPIN) with α- and β-cyclodextrins (CDs) using various analytical techniques. The results indicate that both drugs form 1:1 and 1:2 drug-CD complexes, with excimer emission observed in CD solutions, which enhances their solubility and stability. Molecular modeling and thermodynamic studies support the experimental findings, highlighting the potential of CDs as effective excipients for improving the bioavaila
- Author
- Jun Wei
- Language
- EN