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What is New 5,6-Dihydro-α-Pyrones from Cryptocarya about?

Three new 5,6-dihydro-α-pyrones derivatives and one known pyrone were isolated from the leaves of Cryptocarya pulchrinervia, with their structures elucidated through spectroscopic data and X-ray diffraction analysis. The compounds exhibited varying cytotoxic activities against P-388 cells, with compounds 1-3 showing significant inhibition of cell growth. This study marks the first report of (S)-rugulactone as a natural product and suggests potential for further investigation as anticancer agents.

Author

amoy azimatur

Language

EN