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RNA Exosome Volume 702 by Jensen, Torben Heick is a scholarly article available to read on EtoBox.

What is RNA Exosome Volume 702 about?

The diversity of RNAs inside living cells is amazing. We have known of the more ́ classic ́ RNA species: mRNA, tRNA, rRNA, snRNA and snoRNA for some time now, but in a steady stream new types of molecules are being described as it is becoming clear that most of the genomic information of cells ends up in RNA. To deal with the enormous load of resulting RNA processing and degradation reactions, cells need adequate and efficient molecular machines. The RNA exosome is arising as a major facilitator to this effect. Structural and functional data gathered over the last decade have illustrated the biochemical importance of this multimeric complex and its many co-factors, revealing its enormous regulatory power. By gathering some of the most prominent researchers in the exosome field, it is the aim of this volume to introduce this fascinating protein complex as well as to give a timely and rich account of its many functions. The exosome was discovered more than a decade ago by Phil Mitchell and David Tollervey by its ability to trim the 3 ́ end of yeast, S. cerevisiae, 5. 8S rRNA. In a historic account they laid out the events surrounding this identification and the subsequent birth of

Author

Jensen, Torben Heick

Publisher

Landes Bioscience and Springer Science+Business Media, LLC

Published

2010

Language

EN

ISBN

9781441978400