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Can I read Triply Periodic Minimal Surface-Based Scaffolds for Bone Tissue Engineering: A Mechanical, In Vitro and In Vivo Study on EtoBox?
Triply Periodic Minimal Surface-Based Scaffolds for Bone Tissue Engineering: A Mechanical, In Vitro and In Vivo Study by Ekaterina Maevskaia; Julien Guerrero; Chafik Ghayor; Indranil Bhattacharya; Franz E. Weber is a Medicine article available to read on EtoBox.
What is Triply Periodic Minimal Surface-Based Scaffolds for Bone Tissue Engineering: A Mechanical, In Vitro and In Vivo Study about?
Triply periodic minimal surfaces (TPMSs) are found to be promising microarchitectures for bone substitutes owing to their low weight and superior mechanical characteristics. However, existing studies on their application are incomplete because they focus solely on biomechanical or __in vitro__ aspects. Hardly any __in vivo__ studies where different TPMS microarchitectures are compared have been reported. Therefore, we produced hydroxyapatite-based scaffolds with three types of TPMS microarchitectures, namely Diamond, Gyroid, and Primitive, and compared them with an established Lattice microarchitecture by mechanical testing, 3D-cell culture, and __in vivo__ implantation. Common to all four microarchitectures was the minimal constriction of a sphere of 0.8 mm in diameter, which earlier was found superior in Lattice microarchitectures. Scanning by μCT revealed the precision and reproducibility of our printing method. The mechanical analysis showed significantly higher compression strength for Gyroid and Diamond samples compared with Primitive and Lattice. After __in vitro__ culture with human bone marrow stromal cells in control or osteogenic medium, no differences between these micr
Who reads Triply Periodic Minimal Surface-Based Scaffolds for Bone Tissue Engineering: A Mechanical, In Vitro and In Vivo Study?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Ekaterina Maevskaia; Julien Guerrero; Chafik Ghayor; Indranil Bhattacharya; Franz E. Weber
- Publisher
- Mary Ann Liebert Inc
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)