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Can I read Analysis of the Surgical Approach in Prostate Cancer Staging: Results from the Surveillance, Epidemiology and End Results Program on EtoBox?

Analysis of the Surgical Approach in Prostate Cancer Staging: Results from the Surveillance, Epidemiology and End Results Program by Felipe Andrés Cordero da Luz; Camila Piqui Nascimento; Eduarda da Costa Marinho; Pollyana Júnia Felicidade; Rafael Mathias Antonioli; Rogério Agenor de Araújo; Marcelo José Barbosa Silva is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Analysis of the Surgical Approach in Prostate Cancer Staging: Results from the Surveillance, Epidemiology and End Results Program about?

Surgery is not used as a criterion for staging prostate cancer, although there is evidence that the number of analyzed and affected lymph nodes have prognosis value. The aim of this study was to determine whether there are significant differences in staging criteria in patients who underwent prostatectomy compared to those who did not, and whether the number of affected and analyzed lymph nodes (LN) plays a prognostic role. In this retrospective study, a test cohort consisting of 404,210 newly diagnosed men with prostate cancer, between 2004 and 2010, was obtained from the 17 registries (Nov 2021 submission); a validation consisting of 147,719 newly diagnosed men with prostate cancer between 2004 and 2019 was obtained from the 8 registries (Nov 2021 submission). Prostate cancer-specific survival was analyzed by Kaplan–Meier curves, survival tables and Cox regression; overall survival was analyzed only to compare Harrell's C-index between different staging criteria. In initial analyses, it was observed that the prognostic value of lymph node metastasis changes according to the type of staging (clinical or pathological), which is linked to the surgical approach (prostatectomy). Compa

Who reads Analysis of the Surgical Approach in Prostate Cancer Staging: Results from the Surveillance, Epidemiology and End Results Program?

It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.

Author
Felipe Andrés Cordero da Luz; Camila Piqui Nascimento; Eduarda da Costa Marinho; Pollyana Júnia Felicidade; Rafael Mathias Antonioli; Rogério Agenor de Araújo; Marcelo José Barbosa Silva
Publisher
Springer Science and Business Media LLC
Published
2023
Language
EN
Field
Biochemistry, Genetics and Molecular Biology (Life Sciences)

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