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In Vitro Bioactivity Evaluation of Titanium and Niobium Metals with Different Surface Morphologies by X.J. Wang; Y.C. Li; J.G. Lin; Y. Yamada; P.D. Hodgson; C.E. Wen is a Engineering article available to read on EtoBox.

What is In Vitro Bioactivity Evaluation of Titanium and Niobium Metals with Different Surface Morphologies about?

Current orthopaedic biomaterials research mainly focuses on designing implants that could induce controlled, guided and rapid healing. In the present study, the surface morphologies of titanium (Ti) and niobium (Nb) metals were tailored to form nanoporous, nanoplate and nanofibre-like structures through adjustment of the temperature in the alkali-heat treatment. The in vitro bioactivity of these structures was then evaluated by soaking the treated samples in simulated body fluid (SBF). It was found that the morphology of the modified surface significantly influenced the apatite-inducing ability. The Ti surface with a nanofibre-like structure showed better apatite-inducing ability than the nanoporous or nanoplate surface structures. A thick dense apatite layer formed on the Ti surface with nanofibre-like structure after 1 week of soaking in SBF. It is expected that the nanofibre-like surface could achieve good apatite formation in vivo and subsequently enhance osteoblast cell adhesion and bone formation.

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Author

X.J. Wang; Y.C. Li; J.G. Lin; Y. Yamada; P.D. Hodgson; C.E. Wen

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 1742-7061)

Published

2008

Language

EN

Field

Engineering (Physical Sciences)