Can I read Studies on limb morphogenesis. VI. Experiments with early stages of the polydactylous mutant eudiplopodia on EtoBox?

Studies on limb morphogenesis. VI. Experiments with early stages of the polydactylous mutant eudiplopodia by Robert A. Fraser; Ursula K. Abbott is a Environmental Science article available to read on EtoBox.

What is Studies on limb morphogenesis. VI. Experiments with early stages of the polydactylous mutant eudiplopodia about?

## Abstract Prospective limb mesoderm was transplanted to the flank of twoday host embryos in efforts to study tissue specific effects of the avian polydactylous mutant, eudiplopodia. Initially, normal limb mesoderm was placed in the flank of two‐day scaleless hosts and a scaleless limb resulted, ensuring that the regenerating host ectoderm provided the epithelial covering for the graft limb. Eudiplopod limbs developed from grafts of normal mesoderm to two‐day eudiplopod hosts while the reciprocal combination produced normal limbs. Similar transplants showed that eudiplopod ectoderm may respond to leg mesoderm from both quail and talpid^2^ embryos and does so typically by forming two ridges. Grafts of normal limb mesoderm to three‐and‐one‐half‐day eudiplopod hosts produced supernumerary limbs in the majority of cases whereas most grafts to normal hosts of similar age produced only a skin covered nodule. It is concluded that the mutant gene extends the time of ectodermal competence for ridge formation and that as a consequence of this specificity the mutant effects are seen only in eudiplopod limb ectoderm.

Who reads Studies on limb morphogenesis. VI. Experiments with early stages of the polydactylous mutant eudiplopodia?

Author

Robert A. Fraser; Ursula K. Abbott

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0022-104X)

Published

1971

Language

EN

Field

Environmental Science (Life Sciences)