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What is Residues of Z Terminal about?
This study identifies the first six amino acids of Sonic Hedgehog (Shh) as sufficient for palmitoylation by Hedgehog acyltransferase (Hhat), which is crucial for Shh signaling. The research highlights the importance of specific N-terminal residues in Shh for recognition and modification by Hhat, contributing to our understanding of morphogen processing. The findings may also inform the identification of other potential Hhat substrates in the human genome.
- Author
- Emmaus Tzeng
- Language
- EN