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This document discusses the modular and efficient synthesis of a poly(propylene imine) (PPI) dendron for acid-sensitive doxorubicin conjugation, highlighting its potential for drug delivery applications. The PPI dendron was synthesized with improved scalability and conjugated to doxorubicin, demonstrating fast release at acidic pH and low cytotoxicity against prostate cancer cells. This work presents a promising platform for enhancing targeted drug delivery systems in nanomedicine.
- Author
- nihag56425
- Language
- EN