Can I read RNA-modifying machines in archaea on EtoBox?

RNA-modifying machines in archaea by Arina D. Omer; Sonia Ziesche; Wayne A. Decatur; Maurille J. Fournier; Patrick P. Dennis is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is RNA-modifying machines in archaea about?

## Summary It has been known for nearly half a century that coding and non‐coding RNAs (mRNA, and tRNAs and rRNAs respectively) play critical roles in the process of information transfer from DNA to protein. What is both surprising and exciting, are the discoveries in the last decade that cells, particularly eukaryotic cells, contain a plethora of non‐coding RNAs and that these RNAs can either possess catalytic activity or can function as integral components of dynamic ribonucleoprotein machines. These machines appear to mediate diverse, complex and essential processes such as intron excision, RNA modification and editing, protein targeting, DNA packaging, etc. Archaea have been shown to possess RNP complexes; some of these are authentic homologues of the eukaryotic complexes that function as machines in the processing, modification and assembly of rRNA into ribosomal subunits. Deciphering how these RNA‐containing machines function will require a dissection and analysis of the component parts, an understanding of how the parts fit together and an ability to reassemble the parts into complexes that can function __in vitro__. This article summarizes our current knowledge about small‐

Who reads RNA-modifying machines in archaea?

Author

Arina D. Omer; Sonia Ziesche; Wayne A. Decatur; Maurille J. Fournier; Patrick P. Dennis

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0950-382X)

Published

2003

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)