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Can I read Running Exercise Improves Spatial Learning and Memory Ability and Enhances Angiogenesis in the Cerebral Cortex via Endogenous Nitric Oxide on EtoBox?
Running Exercise Improves Spatial Learning and Memory Ability and Enhances Angiogenesis in the Cerebral Cortex via Endogenous Nitric Oxide by Qianwen Zang; Sanrong Wang; Yinqiang Qi; Lei Zhang; Chunxia Huang; Yun Xiu; Chunni Zhou; Yanmin Luo; Gongwei Jia; Shuangyu Li; Yi Zhang; Yong Tang is a Neuroscience article available to read on EtoBox.
What is Running Exercise Improves Spatial Learning and Memory Ability and Enhances Angiogenesis in the Cerebral Cortex via Endogenous Nitric Oxide about?
Background The molecular mechanisms by which exercise improves brain function and capillaries in the cerebral cortex are unclear. Exercise can increase the expression of nitric oxide (NO) in the brain, and endogenous NO is thought to exert beneficial effects on proangiogenic factors, antiangiogenic factors and brain function. Therefore, we hypothesized that running exercise might improve brain function and enhance angiogenesis through endogenous NO. Methods and results The following three groups of rats were administered intracerebroventricular (i.c.v.) injections before running exercise each day for 4 weeks: exercise+L-NAME group (i.c.v. L-NAME, an NO synthase blocker, dose: 1 μmol/μl and 5 μl/day; treadmill exercise, 20 min/day), exercise group (i.c.v. normal saline, 5 μl/day; treadmill exercise, 20 min/day), and sham group (i.c.v. normal saline, 5 μl/day; no treadmill exercise). Subsequently, the spatial learning and memory abilities were tested using a Morris water maze, and the nitric oxide synthase (NOS) activity in the cerebral cortex in each group of rats was measured using a method involving nitric acid reductase and metabolic chemistry. The parameters of the cortical capi
Who reads Running Exercise Improves Spatial Learning and Memory Ability and Enhances Angiogenesis in the Cerebral Cortex via Endogenous Nitric Oxide?
It is typically read by researchers, students, and practitioners in Neuroscience.
- Author
- Qianwen Zang; Sanrong Wang; Yinqiang Qi; Lei Zhang; Chunxia Huang; Yun Xiu; Chunni Zhou; Yanmin Luo; Gongwei Jia; Shuangyu Li; Yi Zhang; Yong Tang
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Neuroscience (Life Sciences)