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The Association Between Intra-arrest Therapeutic Hypothermia and Return of Spontaneous Circulation Among Individuals Experiencing Out of Hospital Cardiac Arrest by John S. Garrett; Jonathan R. Studnek; Tom Blackwell; Steven Vandeventer; David A. Pearson; Alan C. Heffner; Rosalyn Reades is a Medicine article available to read on EtoBox.
What is The Association Between Intra-arrest Therapeutic Hypothermia and Return of Spontaneous Circulation Among Individuals Experiencing Out of Hospital Cardiac Arrest about?
Introduction: Therapeutic hypothermia has been shown to improve both mortality and neurologic outcomes following pulseless ventricular tachycardia and fibrillation. Animal data suggest intra-arrest induction of therapeutic hypothermia (IATH) improves frequency of return of spontaneous circulation (ROSC). Our objective was to evaluate the association between IATH and ROSC. Methods: This was a retrospective analysis of individuals experiencing non-traumatic cardiac arrest in a large metropolitan area during a 12-month period. Six months into the study a prehospital IATH protocol was instituted whereby patients received 2000 ml of 4 • C normal saline directly after obtaining IV/IO access. The main outcome variables were prehospital ROSC, survival to admission, and to discharge. A secondary analysis was conducted to assess the relationship between the quantity of cold saline infused and the likelihood of prehospital ROSC. Results: 551 patients met inclusion criteria with all the elements available for data analysis. Rates of prehospital ROSC were 36.5% versus 26.9% (OR 1.83; 95% CI 1.19-2.81) in patients who received IATH versus normothermic resuscitation respectively. While the freque
Who reads The Association Between Intra-arrest Therapeutic Hypothermia and Return of Spontaneous Circulation Among Individuals Experiencing Out of Hospital Cardiac Arrest?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- John S. Garrett; Jonathan R. Studnek; Tom Blackwell; Steven Vandeventer; David A. Pearson; Alan C. Heffner; Rosalyn Reades
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0300-9572)
- Published
- 2011
- Language
- EN
- Field
- Medicine (Health Sciences)