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What is Optimized MALDI-MSI for Bone Tissue Analysis about?

This research paper presents an optimized sample preparation protocol for matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) of undecalcified bone tissue, aimed at forensic and preclinical applications. The study demonstrates the effectiveness of a specific embedding composition and sectioning technique for detecting both targeted (methadone and EDDP) and untargeted (lipids) analytes in bone samples from rats, mice, and humans. The developed method enhances the potential for f

Author

alinahassan109

Language

EN