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Chloroquine ## QT interval prolongation: case report A 72-year-old woman developed QT interval prolongation during an off label treatment with chloroquine for COVID-19 viral pneumonia. The woman presented to the emergency department with fever and dyspnoea. Her medical history was significant for paroxysmal atrial fibrillation, for which she had been taking flecainide. At the time of presentation, she was tachypnoeic, her oxygen saturation was 92% and auscultation of the lungs showed bilateral inspiratory crackles and expiratory rhonchi. An ECG revealed sinus rhythm with normal repolarization and a normal QTc interval. She was suspected to have COVID-19 viral pneumonia. Hence, she was admitted to the pulmonology department and started receiving off label treatment with chloroquine 300mg once daily and cefuroxime 1500mg three times daily along with oxygen. Initially, two COVID-19 polymerase chain reaction (PCR) assays were negative. However, 5 days after the admission, she developed respiratory insufficiency and was admitted to the ICU, where mechanical ventilation was initiated. Eventually, COVID-19 infection was confirmed by PCR. She also developed hypotension secondary to deep se

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Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN

Field

Medicine (Health Sciences)