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This document discusses obstructive sleep apnea (OSA), its pathophysiology, effects, and relationship to cardiovascular disease. OSA is defined as repetitive interruptions of breathing during sleep due to collapse of the pharyngeal airway. It discusses how OSA disrupts normal decreases in heart rate, blood pressure, and sympathetic activity during sleep. Mechanisms linking OSA to cardiovascular disease include sympathetic activation, endothelial dysfunction, inflammation, oxidative stress, changes in intrat

Author

Khaled12381

Language

EN