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Clinicopathological Features and Outcomes of Major Salivary Gland Mucoepidermoid Carcinoma: Do They Vary in Different Age Groups by Yujiao Li; Chaosu Hu is a Medicine article available to read on EtoBox.

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## Background The aim of this study was to analyze clinicopathological characteristics and prognostic value of age stratification for in patients with major salivary gland mucoepidermoid carcinoma (MSG-MEC). ## Methods MSG-MEC patients were extracted from the Surveillance, Epidemiology and End Results (SEER) database between 2010 and 2014. We examined the clinicopathological variables using Chi-squared tests. Univariate and multivariate analyses were performed to determine the effects of each variable on survival. ## Results A total of 729 patients were analyzed. Younger patients tended to be female and present with low grade disease and less-advanced N classification (P 1,000), 0.187 (95% CI: 0.041–0.854), 0.172 (95% CI: 0.039–0.771), 0.006 (95% CI: 0.010–0.361), 0.310 (95% CI: 0.140–0.685), 0.541 (95% CI: 0.261–1.121) and 0.440 (95% CI: 0.230–0.840), respectively. Subgroups analysis shows that the effect of advancing age was significantly associated with a higher risk of poor survival in Caucasian who harbored N0 classification (P<0.001), non-metastatic disease (P<0.001) or received surgery (P<0.001). ## Conclusions Younger patients tended to be female and present with low grade

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Author

Yujiao Li; Chaosu Hu

Publisher

AME Publishing Company

Published

2020

Language

EN

Field

Medicine (Health Sciences)