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Pregnancy Outcome of Euploid Fetuses with Increased Nuchal Translucency: How Bad Is the News? by Ron Maymon; Zwi Weinraub; Arie Herman is a Medicine article available to read on EtoBox.

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## Aims: The number of fetuses with an abnormal increased first trimester nuchal translucency (nt), but confirmed normal karyotype and anatomy is relatively small and therefore a challenge for prenatal counseling. universal guidelines are still needed for a systematic work-up, how to decide on the rewarding cut-off for this policy as well as how to counsel patients with an increased nt but with euploid fetuses. the current review aims to address some of these issues. ## Results: Eleven studies reporting on the pregnancy outcome of 2,128 euploid fetuses with increased nt (>or=3 mm or >or=95 centile) were retrieved by our previously reported literature search. 2.2-10.6% of the fetuses has miscarried and 0.5-15.8% ended in perinatal death. there was an overall rate of 0.5-13% neurodevelopmental problems, and 2-8% of the malformations were undiagnosed before birth, the most common being cardiac anomalies. nevertheless, 70-90% fetuses had normal outcomes. ## Conclusion: For those euploid fetuses with increased nt>2 mom or >or=1.5 mm delta nt we recommend a detailed two-step anomaly scan including midgestation fetal echocardiography. maternal age as well as data on relevant family histor

Who reads Pregnancy Outcome of Euploid Fetuses with Increased Nuchal Translucency: How Bad Is the News??

Author

Ron Maymon; Zwi Weinraub; Arie Herman

Publisher

Walter de Gruyter GmbH & Co. KG; Walter de Gruyter GmbH (ISSN 0300-5577)

Published

2005

Language

EN

Field

Medicine (Health Sciences)