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IL-36 Pathway in Pustular Psoriasis by Vostie1811 is a document available to read on EtoBox.
The IL-36 pathway plays an important role in regulating inflammation. Dysfunction of the IL-36 pathway through IL-36 receptor antagonist deficiency or overexpression of IL-36 agonists can lead to autoinflammatory diseases like generalized pustular psoriasis and palmoplantar pustulosis. These conditions are characterized by increased neutrophil infiltration and development of pustules due to uncontrolled inflammatory signaling. While plaque psoriasis and pustular psoriasis have different underlying pathways,
- Author
- Vostie1811
- Language
- EN