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Stilbestrol Effects on DIC in Rats by Akshit Mahajan is a document available to read on EtoBox.
The study investigates the effects of stilbestrol and progesterone on disseminated intravascular coagulation (DIC) in virgin rats following endotoxin infusion. Results showed that stilbestrol significantly augmented DIC, leading to increased glomerular fibrin deposition and decreased plasma fibrinogen levels. The findings suggest that hormonal changes during pregnancy may contribute to a higher susceptibility to DIC, though not solely due to physiological endocrine changes.
- Author
- Akshit Mahajan
- Language
- EN