Can I read Circulating 5α-Dihydrotestosterone, Abdominal Obesity and Adipocyte Characteristics in Women on EtoBox?

Circulating 5α-Dihydrotestosterone, Abdominal Obesity and Adipocyte Characteristics in Women by Julie A. Côté; Julie Lessard; Jacques Mailloux; Philippe Laberge; Caroline Rhéaume; André Tchernof is a Medicine article available to read on EtoBox.

What is Circulating 5α-Dihydrotestosterone, Abdominal Obesity and Adipocyte Characteristics in Women about?

Abstract Background: The association between circulating androgen levels and fat distribution in women has been widely inconsistent among existing studies. ## Objective: We sought to investigate the relation between plasma adrenal and gonadal androgen levels and body fat distribution, as well as abdominal adipocyte characteristics. ## Methods: Paired omental and subcutaneous adipose tissue samples were surgically obtained from 60 women (age, 47±5 years; body mass index, 26±5 kg/m2) undergoing gynecological surgery. body composition and fat distribution were measured by dual-energy x-ray absorptiometry and computed tomography, respectively. adipocyte diameter, basal lipolysis, and heparin-releasable lipoprotein lipase activity were measured. steroids were quantified using high-performance gas chromatography and mass spectrometry. ## Results: Significant negative associations were found between plasma dihydrotestosterone (dht) levels and total adiposity (body mass index, r=-0.35, p<0.05; fat mass, r=-0.31, p<0.05) as well as computed tomography assessments of abdominal adiposity (r=-0.30, p<0.05 and r=-0.44, p<0.005 for subcutaneous and visceral adipose tissue area, respectively). th

Who reads Circulating 5α-Dihydrotestosterone, Abdominal Obesity and Adipocyte Characteristics in Women?

Author

Julie A. Côté; Julie Lessard; Jacques Mailloux; Philippe Laberge; Caroline Rhéaume; André Tchernof

Publisher

Walter de Gruyter GmbH

Published

2012

Language

EN

Field

Medicine (Health Sciences)