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Isolation and antifungal activity of lignans from Myristica fragrans against various plant pathogenic fungi by Jun Young Cho; Gyung Ja Choi; Seung Wan Son; Kyoung Soo Jang; He Kyoung Lim; Sun Og Lee; Nack Do Sung; Kwang Yun Cho; Jin‐Cheol Kim is a Agricultural and Biological Sciences article available to read on EtoBox.

What is Isolation and antifungal activity of lignans from Myristica fragrans against various plant pathogenic fungi about?

## Abstract **BACKGROUND:** In a search for plant extracts with potent __in vivo__ antifungal activity against various plant diseases, we found that treatment with a methanol extract of __Myristica fragrans__ Houttyn (nutmeg) seeds reduced the development of various plant diseases. The objectives of the present study were to isolate and determine antifungal substances from __My. fragrans__ and to evaluate their antifungal activities. **RESULTS:** Three antifungal lignans were isolated from the methanol extract of __My. fragrans__ seeds and identified as __erythro__‐austrobailignan‐6 (EA6), __meso__‐dihydroguaiaretic acid (MDA) and nectandrin‐B (NB). __In vitro__ antimicrobial activity of the three lignans varied according to compound and target species. __Alternaria alternata, Colletotrichum coccodes, C. gloeosporioides, Magnaporthe grisea, Agrobacterium tumefaciens, Acidovorax konjaci__ and __Burkholderia glumae__ were relatively sensitive to the three lignans. __In vivo__, all three compounds effectively suppressed the development of rice blast and wheat leaf rust. In addition, EA6 and NB were highly active against the development of barley powdery mildew and tomato late blight,

Who reads Isolation and antifungal activity of lignans from Myristica fragrans against various plant pathogenic fungi?

It is typically read by researchers, students, and practitioners in Agricultural and Biological Sciences.

Author
Jun Young Cho; Gyung Ja Choi; Seung Wan Son; Kyoung Soo Jang; He Kyoung Lim; Sun Og Lee; Nack Do Sung; Kwang Yun Cho; Jin‐Cheol Kim
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1526-498X)
Published
2007
Language
EN
Field
Agricultural and Biological Sciences (Life Sciences)

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