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A dual propagation contours technique for semi-automated assessment of systolic and diastolic cardiac function by CMR by Wei Feng; Hosakote Nagaraj; Himanshu Gupta; Steven G Lloyd; Inmaculada Aban; Gilbert J Perry; David A Calhoun; Louis J Dell'Italia; Thomas S Denney is a Medicine article available to read on EtoBox.

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## Abstract ## Background Although cardiovascular magnetic resonance (CMR) is frequently performed to measure accurate LV volumes and ejection fractions, LV volume-time curves (VTC) derived ejection and filling rates are not routinely calculated due to lack of robust LV segmentation techniques. VTC derived peak filling rates can be used to accurately assess LV diastolic function, an important clinical parameter. We developed a novel geometry-independent dual-contour propagation technique, making use of LV endocardial contours manually drawn at end systole and end diastole, to compute VTC and measured LV ejection and filling rates in hypertensive patients and normal volunteers. ## Methods 39 normal volunteers and 49 hypertensive patients underwent CMR. LV contours were manually drawn on all time frames in 18 normal volunteers. The dual-contour propagation algorithm was used to propagate contours throughout the cardiac cycle. The results were compared to those obtained with single-contour propagation (using either end-diastolic or end-systolic contours) and commercially available software. We then used the dual-contour propagation technique to measure peak ejection rate (PER) and pea

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Author

Wei Feng; Hosakote Nagaraj; Himanshu Gupta; Steven G Lloyd; Inmaculada Aban; Gilbert J Perry; David A Calhoun; Louis J Dell'Italia; Thomas S Denney

Publisher

BioMed Central; Springer (Biomed Central Ltd.); New York NY: Marcel Dekker; New York N.Y.: Informa Healthcare; London: 2008-; Informa UK Limited; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1097-6647)

Published

2009

Language

EN

Field

Medicine (Health Sciences)