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I) Type I hypersensitivity is anaphylactic or atopic hypersensitivity mediated by IgE antibodies. It involves priming of mast cells and basophils with IgE, cross-linking of surface-bound IgE by re-exposure to antigen, and degranulation resulting in rapid systemic or local effects. II) Type II hypersensitivity is cytotoxic hypersensitivity mediated by IgG or IgM antibodies binding to antigens on cell surfaces, activating the complement system and lysing cells directly or promoting phagocytosis through opso

Author
amitscribd1
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