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Long‐term outcomes of self‐expanding versus balloon‐expandable transcatheter aortic valves: Insights from the OBSERVANT study by Giuliano Costa; Paola D'Errigo; Stefano Rosato; Roberto Valvo; Fausto Biancari; Corrado Tamburino; Francesco Cerza; Stefano Domenico Cicala; Fulvia Seccareccia; Marco Barbanti; for the OBSERVANT Research Group is a Medicine article available to read on EtoBox.

What is Long‐term outcomes of self‐expanding versus balloon‐expandable transcatheter aortic valves: Insights from the OBSERVANT study about?

## Abstract ## Objectives To compare clinical outcomes of balloon‐expandable (BE) and self‐expanding (SE) transcatheter aortic valves (TAVs) up to 5 years. ## Background To date, no robust, comparative data of BE and SE TAVs at long‐term are available. ## Methods We considered a total of 1,440 patients enrolled in the multicenter OBSERVANT study and undergoing transfemoral transcatheter aortic valve implantation (TF‐TAVI) with either supra‐annular SE (n = 830, 57.6%) and intra‐annular BE (n = 610, 42.4%) valves. Clinical outcomes of the two groups were compared after adjustment using inverse probability of treatment weighting (IPTW) and confirmed by sensitivity analysis with propensity score matching. ## Results Patients receiving SE valve showed a higher all‐cause mortality at 5 years (Kaplan–Meier estimates 52.3% vs. 47.7%; Hazard ratio [HR] 1.18, 95% confidence interval [CI] 1.01–1.38, p = .04). Landmark analyses showed that there was a not statistically significant reversal of risk excess against the BE group starting from 3 years after TAVI (3–5 years HR 0.97, 95% CI 0.76–1.25, p = .86). Post‐procedural, moderate/severe paravalvular regurgitation (PVR)(HR 1.46, 95% CI 1.14–1.8

Who reads Long‐term outcomes of self‐expanding versus balloon‐expandable transcatheter aortic valves: Insights from the OBSERVANT study?

Author

Giuliano Costa; Paola D'Errigo; Stefano Rosato; Roberto Valvo; Fausto Biancari; Corrado Tamburino; Francesco Cerza; Stefano Domenico Cicala; Fulvia Seccareccia; Marco Barbanti; for the OBSERVANT Research Group

Publisher

Wiley

Published

2021

Language

EN

Field

Medicine (Health Sciences)