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Augmenting antidepressant medication with modular CBT for geriatric generalized anxiety disorder: a pilot study by Julie Loebach Wetherell; Jill A. Stoddard; Kamila S. White; Sander Kornblith; Hoang Nguyen; Carmen Andreescu; Sidney Zisook; Eric J. Lenze is a Medicine article available to read on EtoBox.
What is Augmenting antidepressant medication with modular CBT for geriatric generalized anxiety disorder: a pilot study about?
## Abstract ## Objective Generalized anxiety disorder (GAD) is a prevalent psychiatric condition in older adults with deleterious effects on health and cognition. Although selective serotonin reuptake inhibitor (SSRI) medications have some efficacy as acute treatments for geriatric GAD, incomplete response is the most common outcome of monotherapy. We therefore developed a novel sequential treatment strategy, using personalized, modular cognitive‐behavioral therapy (mCBT) to augment SSRI medication. ## Method In an open label pilot study (__N__= 10), subjects received a sequenced trial of 12 weeks of escitalopram followed by 16 weeks of escitalopram augmented with mCBT. We also examined the maintenance effects of mCBT over a 28‐week follow‐up period following drug discontinuation and termination of psychotherapy. ## Results Results suggest that (1) adding mCBT to escitalopram significantly reduced anxiety symptoms and pathological worry, resulting in full remission for most patients and (2) some patients maintained response after all treatments were withdrawn. ## Conclusion Findings suggest that mCBT may be an effective augmentation strategy when added to SSRI medication and provid
Who reads Augmenting antidepressant medication with modular CBT for geriatric generalized anxiety disorder: a pilot study?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Julie Loebach Wetherell; Jill A. Stoddard; Kamila S. White; Sander Kornblith; Hoang Nguyen; Carmen Andreescu; Sidney Zisook; Eric J. Lenze
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0885-6230)
- Published
- 2010
- Language
- EN
- Field
- Medicine (Health Sciences)