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The study investigates the expression of cytotoxicity-related receptors on γδ T cells in chronic lymphocytic leukaemia (CLL) patients, revealing higher levels of CD56 and LAG-3, and lower levels of CD16 compared to healthy controls. Subgroup analysis indicates that ZAP-70-negative patients show increased CD69, while CD38-negative patients have higher CD16 expression, with CD16 inversely correlated with serum LDH levels. The findings suggest altered γδ T cell receptor expression may play a role in CLL progre

Author
gustavoamariz7
Language
EN