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Excision of pyrimidine dimers by several UV-sensitive mutants of S. pombe by H. C. Birnboim; A. Nasim is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

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Nine radiation-sensitive mutants of S. pombe showing a variety of phenotypic characteristics were analysed for their ability to excise pyrimidine dimers after ultraviolet irradiation. From earlier studies using indirect parameters, it was expected that some would be excision-deficient. Data reported here show that all the mutants tested, like wild type cells, were able to remove a high percentage of pyrimidine dimers during post-irradiation incubation in several different holding media, but not in saline or phosphate buffer. These mutants included strains showing increased, as well as others which showed decreased, levels of UV-induced mutation frequency relative to that of the wild type at the same total dose.

Who reads Excision of pyrimidine dimers by several UV-sensitive mutants of S. pombe?

Author

H. C. Birnboim; A. Nasim

Publisher

Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC (ISSN 0026-8925)

Published

1975

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)