About this Medicine article
Evidence for Superior Efficacy and Safety of LASIK over Photorefractive Keratectomy for Correction of Myopia by Alex J. Shortt; Catey Bunce; Bruce D.S. Allan is a Medicine article available to read on EtoBox.
Purpose To examine possible differences in efficacy and safety between LASIK and photorefractive keratectomy (PRK) for correction of myopia. Design Meta-analysis/systematic review. Participants Patient data from previously reported prospective randomized controlled trials (PRCTs) and a systematic review of prospective case series in the Food and Drug Administration (FDA) clinical trials database. Methods A comprehensive literature search was performed using the Cochrane Collaboration methodology to identify PRCTs comparing LASIK and PRK for correction of myopia. A meta-analysis was performed on the results of PRCTs. In parallel, a systematic review of prospective data from FDA case series of LASIK and PRK for correction of myopia was undertaken. Main Outcome Measures Key efficacy outcomes (uncorrected visual acuity [UCVA] ≥ 20/20, ±0.50 diopters [D] of the target mean refractive spherical equivalent) and safety outcomes (loss of ≥2 lines of best spectacle-corrected visual acuity [BSCVA], final BSCVA ≥ 20/40, and final BSCVA < 20/25 where preoperative BSCVA was ≥20/20). Results Seven PRCTs were identified comparing PRK (683 eyes) and LASIK (403 eyes) for correction of myopia. More L
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Alex J. Shortt; Catey Bunce; Bruce D.S. Allan
- Publisher
- Elsevier BV
- Published
- 2006
- Language
- EN
- Field
- Medicine (Health Sciences)