Can I read Bioinformatical Approaches to the Discovery and Classification of Novel Deubiquitinases on EtoBox?

Bioinformatical Approaches to the Discovery and Classification of Novel Deubiquitinases by Thomas Hermanns; Kay Hofmann is a book available to read on EtoBox.

What is Bioinformatical Approaches to the Discovery and Classification of Novel Deubiquitinases about?

Ubiquitination regulates a wide variety of cellular processes, including protein stability, vesicular trafficking, autophagy, inflammation, and the cellular defense against invading pathogens [ ]. Deubiquitinating enzymes (DUBs) are proteases, which specifically cleave peptide or isopeptide bonds formed by the C-terminus of ubiquitin and have several important roles in the eukaryotic ubiquitin system. Among other tasks, DUBs are crucial for ubiquitin activation and for maintaining cellular ubiquitin levels, but they also break ubiquitin chains and can edit or even remove ubiquitin conjugates from their substrates [ ]. Deubiquitinaseslike other components of the ubiquitin systemare found in all eukaryotes. In addition, many DUBs are also encoded by intracellular pathogens such as 2 1

Author

Thomas Hermanns; Kay Hofmann

Publisher

Springer US : Imprint: Humana

Published

2023

Language

EN

ISBN

9781071628027

Subjects

Science, Stem