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What is DNA Repair Mechanisms in Cancer about?
Cancers arise from mutations in DNA that can be caused by errors in DNA repair. There are several pathways that repair different types of DNA damage, including base excision repair, nucleotide excision repair, and mismatch repair. Defects in DNA repair genes can lead to increased mutations and cancer predisposition syndromes. Double-strand break repair is especially important as errors can cause chromosomal rearrangements and instability driving cancer.
- Author
- dw
- Language
- EN