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Can I read Ga-DOTA-TOC: The First FDA-Approved ^68^Ga-Radiopharmaceutical for PET Imaging on EtoBox?

Ga-DOTA-TOC: The First FDA-Approved ^68^Ga-Radiopharmaceutical for PET Imaging by Hennrich, Ute; Benešová, Martina is a Medicine article available to read on EtoBox.

What is Ga-DOTA-TOC: The First FDA-Approved ^68^Ga-Radiopharmaceutical for PET Imaging about?

In the United States, [^68^Ga]Ga-DOTA-TOC has been approved by the Food and Drug Administration (FDA) in 2019 as the first ^68^Ga-radiopharmaceutical for imaging of somatostatin receptor (SSTR) positive gastroenteropancreatic neuroendocrine tumors while employing positron emission tomography (PET). In Europe (Austria, Germany, France), [^68^Ga]Ga-DOTA-TOC was already approved back in 2016. This radiopharmaceutical combines the radionuclide ^68^Ga with the somatostatin analogue DOTA-TOC for specific imaging of tumor cells expressing SSTRs. Such a targeting approach can also be used for therapy planning in the case of both localized as well as disseminated disease and potentially for the evaluation of treatment response.

Who reads Ga-DOTA-TOC: The First FDA-Approved ^68^Ga-Radiopharmaceutical for PET Imaging?

It is typically read by researchers, students, and practitioners in Medicine.

Author
Hennrich, Ute; Benešová, Martina
Publisher
MDPI AG; Multidisciplinary Digital Publishing Institute (MDPI); Basel: MDPI Molecular Diversity Preservation International, 2004- (ISSN 1424-8247)
Published
2020
Language
EN
Field
Medicine (Life Sciences)

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