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Progress in cancer chemoprevention: Agents by Charles W. Boone; Ming You is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Progress in cancer chemoprevention: Agents about?

Collaborative chemoprevention projects between the United States (US), China, Korea, and Japan are desirable because each country contributes significant specialized resources and expertise, making the projects proceed more rapidly than they could in any one country alone. The US offers experience in managing short-term Phase II chemoprevention trials, and experience in quantitative measurement of surrogate endpoint biomarkers, including molecular markers, in tissue and cytologic samples, using computer-assisted image analysis to increase precision and objectivity. Japan has multiple research activities related to the discovery of new chemopreventive agents, particularly those from food, and a pharmaceutical industry capable of supplying new and innovative drugs in the kilogram amounts required for clinical toxicology testing and clinical trials. Chinese and Korean research institutes have identified many cohorts with premalignant lesions suitable for chemopreventive intervention. Examples of such cohorts of interest are ductal carcinoma in situ of the breast, oral leukoplakia, respiratory metaplasia and dysplasia, colon polyps, low-stage bladder and prostate neoplasms, prostatic i

Who reads Progress in cancer chemoprevention: Agents?

Author

Charles W. Boone; Ming You

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0730-2312)

Published

1997

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)