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Testosterone Disorders and Male Hypogonadism in Kidney Disease by Giacomo Garibotto; Pasquale Esposito; Daniela Picciotto; Daniela Verzola is a Medicine article available to read on EtoBox.

What is Testosterone Disorders and Male Hypogonadism in Kidney Disease about?

Chronic kidney disease (CKD) causes substantial alterations in the male endocrine system, which affect puberty, libido, and sexual function. A major effect of CKD is a reduction in testosterone levels because of both primary and hypogonadotrophic hypogonadism. In addition to impairment of pubertal growth and sexual maturation in children with CKD, clinical evidence suggests that uremic hypogonadism strongly contributes to several CKD complications, including erectile dysfunction, muscle wasting and frailty, anemia, decreased bone mineralization, depression, and cognitive impairment. This review focuses on a reappraisal of the physiologic role of testosterone, with an emphasis on the hypogonadal condition linked to CKD and its complications.

Who reads Testosterone Disorders and Male Hypogonadism in Kidney Disease?

Author

Giacomo Garibotto; Pasquale Esposito; Daniela Picciotto; Daniela Verzola

Publisher

Elsevier BV

Published

2021

Language

EN

Field

Medicine (Health Sciences)