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Overview of Toll-Like Receptors by Pablo Vera Otero is a document available to read on EtoBox.
What is Overview of Toll-Like Receptors about?
Toll-like receptors (TLRs) recognize distinct pathogen-associated molecular patterns. TLRs signal through either a MyD88-dependent or independent pathway to activate transcription factors that induce inflammatory responses. The MyD88-dependent pathway involves the adaptor MyD88 recruiting a kinase complex that phosphorylates NF-κB and MAP kinases, leading to production of pro-inflammatory cytokines. TLR4 additionally signals through a MyD88-independent pathway utilizing the adaptors TRIF and TRAM to induce
- Author
- Pablo Vera Otero
- Language
- EN