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A comparative study of once‐daily versus twice‐daily filgrastim administration for the mobilization and collection of CD34^+^ peripheral blood progenitor cells in normal donors by Paolo Anderlini; Michele Donato; Mary J. Lauppe; Yang O. Huh; Thomas G. Martin; Ka-Wah Chan; Richard E. Champlin; Martin Körbling is a Medicine article available to read on EtoBox.

What is A comparative study of once‐daily versus twice‐daily filgrastim administration for the mobilization and collection of CD34^+^ peripheral blood progenitor cells in normal donors about?

Eighty‐one first‐time normal donors underwent leukapheresis for peripheral blood progenitor cell (PBPC) collection after mobilization with filgrastim administered either twice‐daily (6 μg/kg every 12 h; __n__ = 40) or once‐daily (12 μg/kg; __n__ = 41) subcutaneously for 3 d. The groups were similar for age, donor blood volume and target CD34^+^ cell dose to be collected (≥ 4 × 10^6^ CD34^+^ cells/kg recipient). There was no statistically significant difference in the apheresis yield of CD34^+^ PBPCs (× 10^6^) per kg recipient weight (5·6 ± 3·3 vs. 5·6 ± 4·3; __P__ = 0·94) and per litre of blood processed (30 ± 17·2 vs. 30·4 ± 19·5; __P__ = 0·92).

Who reads A comparative study of once‐daily versus twice‐daily filgrastim administration for the mobilization and collection of CD34^+^ peripheral blood progenitor cells in normal donors?

It is typically read by researchers, students, and practitioners in Medicine.

Author
Paolo Anderlini; Michele Donato; Mary J. Lauppe; Yang O. Huh; Thomas G. Martin; Ka-Wah Chan; Richard E. Champlin; Martin Körbling
Publisher
John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0007-1048)
Published
2000
Language
EN
Field
Medicine (Health Sciences)

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