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Multiexponential T2 relaxation in degenerating peripheral nerve by Mark D. Does; Richard E. Snyder is a Medicine article available to read on EtoBox.

What is Multiexponential T2 relaxation in degenerating peripheral nerve about?

## Abstract The multiexponential __T__~2~ relaxation spectrum of peripheral nerve undergoing Wallerian degeneration has been measured both __in vivo__ and __in vitro.__ Degeneration of the sciatic nerve of the amphibian __Xenopus laevis__ was induced by crush injury, and __T__~2~ relaxation spectra of the nerve were measured at several times up to 35 days following injury. Histologic evidence verified that the nerve underwent Wallerian degeneration. Relaxation spectra were observed to undergo measurable changes as degeneration progressed, the most evident being a reduction from three well‐resolved __T__~2~ components to one and a decline in the fraction of the spectra associated with the shortest __T__~2~ component The former appears to reflect the collapse and loss of myelinated fibers, while the latter a combination of interstitial edema and myelin loss.

Who reads Multiexponential T2 relaxation in degenerating peripheral nerve?

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Author
Mark D. Does; Richard E. Snyder
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0740-3194)
Published
1996
Language
EN
Field
Medicine (Health Sciences)

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