Opening book details…
Can I read Histopathological and histomorphometric investigation of the effects of different irrigation solutions on Achilles tendon healing in rats on EtoBox?
Histopathological and histomorphometric investigation of the effects of different irrigation solutions on Achilles tendon healing in rats by Yaşar Mahsut Dincel; Erdem Can; Sevil Karabag is a Medicine article available to read on EtoBox.
What is Histopathological and histomorphometric investigation of the effects of different irrigation solutions on Achilles tendon healing in rats about?
## Objectives This study aimed to examine the effect of irrigation fluids containing povidone-iodine (PVP-I), rifampicin (RF), and chlorhexidine gluconate (CHG) used during surgery on healing on a rat Achilles tendon model. ## Materials and methods Twenty-eight male Sprague-Dawley rats (range, 300 to 400 g) were used in the experiment carried out between November 2022 and December 2022. The rats were divided into PVP-I, RF, CHG, and control groups, with seven rats in each group. Following the tenotomy and repair of the right Achilles tendon, the surgical site was irrigated using PVP-I, RF, CHG, or normal saline (the control group) for 2 min. All rats were sacrificed on the 21^st^ postoperative day. The samples were evaluated histomorphometrically using the scoring system modified by Svensson, Soslowsky, and Cook and histopathologically using the Bonar and Movin classifications. ## Results The RF group gave better results in all three scoring systems compared to the control, PVP-I, and CHG groups (p=0.008, p=0.002, and p=0.006, respectively). Cellularity, rounding, and tenocyte morphology showed a significant difference in favor of the RF group (p=0.004). While the distribution of g
Who reads Histopathological and histomorphometric investigation of the effects of different irrigation solutions on Achilles tendon healing in rats?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Yaşar Mahsut Dincel; Erdem Can; Sevil Karabag
- Publisher
- Bayçınar Medical Publishing
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)
More by Yaşar Mahsut Dincel; Erdem Can; Sevil Karabag
Browse all works by Yaşar Mahsut Dincel; Erdem Can; Sevil Karabag